Endometriosis is a chronic condition that can severely affect fertility, particularly when ovarian reserve and egg quality are compromised. For some women, egg donation (ovodonation) represents a hopeful, effective path toward achieving pregnancy when other treatments have not succeeded. In this article, we explore when ovodonation is indicated in patients with endometriosis, what the process …
Endometriosis is a chronic condition that can severely affect fertility, particularly when ovarian reserve and egg quality are compromised. For some women, egg donation (ovodonation) represents a hopeful, effective path toward achieving pregnancy when other treatments have not succeeded.
In this article, we explore when ovodonation is indicated in patients with endometriosis, what the process involves, and how EndoGlobal supports women through this journey with compassion and scientific precision.
How Endometriosis Affects Fertility
Endometriosis impacts fertility in several ways:
Ovarian damage: Endometriomas (ovarian cysts caused by endometriosis) can reduce ovarian reserve and affect egg quality.
Inflammation: Chronic pelvic inflammation can impair fertilization and implantation.
Distorted anatomy: Adhesions and lesions may interfere with ovulation or the function of the fallopian tubes.
Repetitive surgeries: Multiple ovarian surgeries may further compromise ovarian reserve.
Age factor: As women with endometriosis delay pregnancy, age-related decline in egg quality adds to the challenge.
When Is Egg Donation Recommended in Endometriosis?
Egg donation is not a first-line treatment for endometriosis-related infertility. However, it becomes a highly effective option in specific cases:
1. Severely diminished ovarian reserve
Women with low anti-Müllerian hormone (AMH) levels and poor response to stimulation—especially after previous failed IVF cycles—may benefit more from ovodonation than from repeated use of their own eggs.
2. Recurrent IVF failure with own eggs
Even with normal ovarian reserve, some women experience repeated IVF failure due to poor egg quality. Egg donation may offer a better chance of implantation and live birth.
3. Advanced endometriosis with bilateral endometriomas or prior ovarian surgeries
If both ovaries have been affected and surgically treated, the likelihood of retrieving good-quality eggs is significantly lower.
4. Age over 40 with active or past endometriosis
Age already reduces the chances of pregnancy with own eggs. When combined with endometriosis, egg donation often becomes the most realistic and time-efficient option.
What Does the Egg Donation Process Involve?
At EndoGlobal, ovodonation is conducted under strict medical, ethical, and legal standards. The process typically includes:
Recipient preparation:
The intended mother undergoes endometrial preparation with estrogen and progesterone to synchronize her cycle with the donor’s.
Donor selection:
Egg donors are healthy, young women thoroughly screened for physical health, infectious diseases, psychological wellness, and genetic conditions.
Fertilization and embryo transfer:
The donor’s eggs are fertilized with the recipient’s partner’s sperm (or donor sperm, if applicable), and a high-quality embryo is transferred to the recipient’s uterus.
Cryopreservation:
Surplus embryos can be vitrified for future attempts.
Success Rates and Emotional Considerations
Egg donation is one of the most successful assisted reproduction treatments available today. Success rates often exceed 60–70% per cycle, depending on age and uterine health.
That said, ovodonation can bring emotional and psychological challenges for some women, particularly when the use of one’s own eggs was central to their identity as a future parent. At EndoGlobal, we provide full psychological counseling and emotional support before, during, and after treatment.
What Makes EndoGlobal Different?
At EndoGlobal, we specialize in fertility care for women with endometriosis. Our approach to ovodonation is:
Multidisciplinary: Reproductive specialists, surgeons, psychologists, and coordinators work together.
Patient-centered: Every case is reviewed individually, respecting personal values and reproductive goals.
Ethical and transparent: Our donation process meets national and international standards.
We understand that choosing egg donation is a big step—and we walk with you every part of the way.
Final Thoughts
Egg donation is not a sign of defeat—it is a path of hope. For many women with endometriosis, it becomes the most effective and emotionally fulfilling way to build a family after years of struggle.
At EndoGlobal, we offer experience, empathy, and excellence in helping you achieve your dream of motherhood.
EndoGlobal – Where science meets compassion.
